Expresión de búsqueda:
RECEPTOR, SEROTONIN, 5-HT1D
Descriptores Encontrados:
1
Mostrando:
1 .. 1
1 / 1
DeCS
Descriptor
Inglés
:
Receptor, Serotonin, 5-HT1D
Descriptor
Español
:
Receptor de Serotonina 5-HT1D
Descriptor
Portugués
:
Receptor 5-HT1D de Serotonina
Sinónimos
Inglés
:
Serotonin 1D Receptor
Categoría:
D12.776.543.750.070.800.100.200
D12.776.543.750.100.800.100.200
D12.776.543.750.720.300.800.100.200
D12.776.543.750.720.670.100.750
Definición
Inglés
:
A
serotonin
receptor subtype that is localized to the
CAUDATE NUCLEUS
;
PUTAMEN
; the
NUCLEUS ACCUMBENS
; the
HIPPOCAMPUS
, and the
RAPHE NUCLEI
. It plays a
role
as a terminal autoreceptor that regulates the rate of
SEROTONIN
release from
nerve endings
. This
serotonin
receptor subtype is closely related to and has
similar
drug binding properties as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive to the agonist
SUMATRIPTAN
and may be involved in mediating the drug's antimigrane effect.
Nota Histórica
Inglés
:
2004; use RECEPTOR, SEROTONIN, 5-HT1D (NM) 1996-2003
Calificadores Permitidos
Inglés
:
administration & dosage
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
chemistry
classification
drug effects
deficiency
genetics
history
immunology
isolation & purification
metabolism
physiology
radiation effects
therapeutic use
ultrastructure
Número del Registro:
38305
Identificador Único:
D044346
Ocurrencia en la BVS
:
Similar:
DeCS
SciELO
LILACS
LIS